Sculptra — PLLA Collagen Biostimulator 2 Vials
- FDA-approved PLLA collagen biostimulator by Galderma (USA/France)
- 2 vials per box — 150mg PLLA per vial (367.5mg freeze-dried powder total)
- Reconstituted with sterile water — requires preparation before injection
- Gradual neocollagenesis — natural-looking results over weeks to months
- Results last up to 2 years — one of the longest-lasting biostimulators
- Decades of clinical use and proven safety profile
| 1 - 2 vials | $472.50 / box |
| 3 - 9 vials | $448.88 / box |
| 10 - 19 vials | $425.25 / box |
| 20 - 29 vials | $411.08 / box |
| 30+ vials | $396.90 / box |
What Is Sculptra — PLLA Collagen Biostimulator 2 Vials?
Sculptra is an FDA-approved PLLA (poly-L-lactic acid) collagen biostimulator manufactured by Galderma (USA/France). Supplied as 2 lyophilized vials per box, each containing 367.5mg freeze-dried powder including 150mg PLLA microparticles. Reconstituted with sterile water for injection before use. Rather than providing immediate gel volume, Sculptra stimulates gradual neocollagenesis through a controlled biological response, delivering natural-looking facial volume restoration over a series of treatments with results lasting up to 2 years.
Sculptra is the original PLLA biostimulator with FDA approval and decades of clinical use worldwide. Unlike HA fillers that provide immediate volume, Sculptra works by stimulating the body's own collagen production. Its PLLA microparticles trigger a controlled response that builds natural-looking volume progressively over weeks to months. Supplied as 2 lyophilized vials per box (150mg PLLA per vial), reconstituted with sterile water before injection. Results can last up to 2 years, making it one of the longest-lasting collagen biostimulators available.
Specifications
| Product name | Sculptra (Galderma, USA/France) |
|---|---|
| Type | PLLA collagen biostimulator |
| Active ingredient | Poly-L-lactic acid (PLLA) microparticles 150mg per vial |
| Format | Lyophilized freeze-dried powder |
| Box contents | 2 vials per box |
| Total powder weight | 367.5mg per vial (includes PLLA + carrier) |
| Reconstitution | Sterile water for injection - agitate until evenly suspended |
| Mechanism | Controlled subclinical response - gradual neocollagenesis |
| Injection depth | Deep dermis / subcutaneous |
| Treatment course | Series of sessions spaced several weeks apart |
| Onset | Progressive - weeks to months |
| Duration | Up to 2 years |
| Treatment areas | Facial volume restoration, cheeks, temples, jawline, chin |
| Origin | USA / France (Galderma) |
| Certification | FDA, CE |
| Storage | Room temperature (15-25 C) before reconstitution |
| Shelf life | 24 months |
Key Benefits
- Long-lasting - results persist up to 2 years, significantly longer than HA fillers, reducing touch-up frequency
- Natural progression - volume builds gradually as new collagen forms, avoiding abrupt changes in appearance
- FDA-approved - backed by extensive clinical studies and decades of real-world use worldwide
- Pure biostimulation - does not rely on gel volume, so results come entirely from the body's own collagen
- Versatile treatment - suitable for multiple facial areas including cheeks, temples, jawline, and chin
- Proven technology - PLLA has been used safely in medical applications for over 20 years
Suggested Treatment Protocol
Sculptra is supplied as a lyophilized powder requiring reconstitution with sterile water for injection before use. Agitate thoroughly until the powder is evenly suspended. Lidocaine may be added per protocol for patient comfort. Administered as a series of treatments (typically 2-3 sessions) spaced several weeks apart. Injected into the deep dermis or subcutaneous layer by a licensed practitioner. Massage the treated area as directed. Results develop progressively as new collagen is formed over weeks to months. Final outcome is visible after the complete treatment series and can last up to 2 years.
Frequently Asked Questions
How is Sculptra different from HA fillers?
Sculptra is a pure biostimulator - it does not provide immediate gel volume like HA fillers. Instead, its PLLA microparticles trigger the body to produce its own collagen gradually over time. Results are more natural because they develop progressively, and they last significantly longer (up to 2 years vs 6-18 months for HA).
How many sessions of Sculptra are typically needed?
Most patients require 2-3 treatment sessions spaced several weeks apart. The exact number depends on the area being treated, the degree of correction needed, and the individual patient response to collagen stimulation.
How long do Sculptra results last?
Results can last up to 2 years from the start of treatment. Because Sculptra stimulates the body's own collagen, the results are biological and progressive - they build over months and are longer-lasting than HA-based fillers.
Does Sculptra require reconstitution?
Yes - Sculptra is a lyophilized (freeze-dried) powder that must be reconstituted with sterile water for injection before use. The vial should be agitated thoroughly until the powder is evenly suspended before injection.
Is Sculptra FDA approved?
Yes - Sculptra is FDA-approved for facial volume restoration and has been used clinically for decades. It is manufactured by Galderma (USA/France) and is one of the most well-studied biostimulators available.
Reliable product with predictable results. The learning curve for proper reconstitution and injection is worth it. Results at 12 months are still very visible. Would recommend for experienced practitioners.
Works beautifully for cheek volume restoration. The reconstitution protocol is straightforward and the injection technique is well established. Good option for patients wanting natural, gradual improvement.
Excellent for full-face volume restoration. The series approach means results look completely natural. My patients appreciate that the improvement is gradual and subtle. Lasts well over 18 months in my experience.
The gold standard in PLLA biostimulation. I've been using Sculptra for years and the results are consistently excellent. The gradual collagen buildup gives very natural-looking volume restoration. Patients love the longevity.
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