Biostimulatory Fillers

Rejubella 300mg — PDO Microsphere Collagen Biostimulator Powder

5.00 (1 reviews) SKU: CYT-BSF-REJUBELLA-300MG
Rejubella 300mg is a polydioxanone (PDO) microsphere collagen biostimulator supplied as a lyophilized powder. PDO microspheres stimulate fibroblast activity to promote Type I/III collagen regeneration, supporting facial volume and skin quality. Manufactured by Metabiomed, South Korea. For licensed professionals only.
  • PDO (polydioxanone) microsphere collagen biostimulator — gradual neocollagenesis
  • 300mg per vial, lyophilized powder for reconstitution
  • Stimulates Type I and Type III collagen regeneration via fibroblast activation
  • Uniform microspheres (10–60μm) for even tissue distribution
  • Same biodegradable PDO material as lifting threads — in injectable microsphere format
  • Made in South Korea by Metabiomed — For licensed professionals only
$113.50 / box · USD
Wholesale Volume Pricing
1 – 2 boxes$113.50 / vial
3 – 9 boxes$107.83 / vial
10 – 19 boxes$102.15 / vial
20 – 29 boxes$98.75 / vial
30+ boxesContact for quote
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What Is Rejubella 300mg — PDO Microsphere Collagen Biostimulator Powder?

Rejubella 300mg is a polydioxanone (PDO) microsphere collagen biostimulator from Metabiomed (South Korea), containing 300mg of uniform PDO microspheres per vial for reconstitution and dermal injection.

Rejubella brings the collagen-stimulating action of PDO (polydioxanone) into an injectable microsphere format. PDO is a well-established biodegradable polymer long used in surgical sutures and lifting threads. In Rejubella, the PDO is formulated as uniform microspheres that can be distributed evenly through the tissue, prompting fibroblasts to produce new Type I and Type III collagen. The microspheres are then gradually broken down and resorbed by the body, leaving the newly formed collagen behind — supporting both volume restoration and overall skin quality.

Specifications

Product nameRejubella 300mg
BrandRejubella (Metabiomed)
TypePDO microsphere collagen biostimulator
Active ingredientPolydioxanone (PDO) microspheres (10–60μm)
CarrierCarboxymethylcellulose (CMC)
Strength300 mg per vial
Presentation300 mg × 1 vial, powder for reconstitution
PreparationReconstitute before use per product instructions until even suspension forms
Injection depthDermis
MechanismPDO microsphere collagen stimulation (Type I/III collagen regeneration)
DurationCollagen-based results develop gradually over weeks following treatment
Treatment areasFacial volume restoration, nasolabial folds, marionette lines, cheek augmentation, skin rejuvenation and quality improvement
OriginSouth Korea (Metabiomed)
StorageStore per product labeling. Protect from moisture. Do not freeze reconstituted suspension.
Shelf life24 months from manufacture date

Key Benefits

  • PDO microspheres leverage the same proven biocompatible material used in surgical sutures and lifting threads for predictable collagen stimulation
  • Gradual, natural-looking collagen regeneration produces progressive volume and skin quality improvement without sudden changes
  • Uniform spherical microspheres (10–60μm) enable consistent, even distribution throughout the treatment area for balanced results
  • Fully biodegradable — PDO is gradually metabolised and resorbed by the body, leaving newly formed collagen as the lasting result
  • Versatile applications ranging from facial volume restoration to overall skin rejuvenation and quality improvement

Suggested Treatment Protocol

Rejubella 300mg is supplied as a lyophilized powder that must be reconstituted before use. Reconstitute the powder per the product instructions until an even suspension of microspheres forms. The reconstituted suspension is injected into the dermis by a licensed practitioner for collagen stimulation and skin support. A course of sessions may be advised based on the patient's skin condition and aesthetic goals. As with all collagen biostimulators, correct preparation, injection plane and technique are essential to reduce the risk of delayed nodules or foreign-body reactions.

For professional use only. This product is intended for purchase and administration by licensed medical or aesthetic practitioners in accordance with local regulations.

Frequently Asked Questions

What is Rejubella 300mg?

Rejubella 300mg is a polydioxanone (PDO) microsphere collagen biostimulator supplied as a 300mg powder for reconstitution, used to stimulate the skin's own collagen for gradual rejuvenation.

What is PDO?

Polydioxanone (PDO) is a biodegradable polymer long used in surgical sutures and lifting threads. In Rejubella, it is formulated as uniform microspheres for injectable collagen stimulation.

How is Rejubella different from PDO threads?

Both use PDO, but Rejubella delivers it as injectable microspheres distributed through the tissue rather than as physical threads, providing broader, more even collagen stimulation.

How is Rejubella prepared?

It is a lyophilized powder reconstituted before use per the product instructions, until an even suspension of microspheres forms.

When will results appear?

Results develop gradually over the weeks following treatment as the PDO microspheres stimulate new collagen formation.

Who can administer Rejubella?

Licensed, trained practitioners only, using appropriate reconstitution and injection technique with knowledge of facial anatomy.

5.0
Based on 1 review
Olivia Wang
July 4, 2026

Used Rejubella 300mg — PDO Microsphere Collagen Biostimulator Powder on several patients last month. The gradual, natural-looking collagen regeneration produces progressive volume and performs as described. Will keep ordering.