Olidia® PLLA 365mg — PLLA Collagen Biostimulator Lyophilized Powder
- PLLA (poly-L-lactic acid) collagen biostimulator — gradual neocollagenesis
- 365mg per vial (PLLA 150mg + CMC 90mg + Mannitol 125mg), lyophilized powder
- Reconstitute with ~9mL sterile water before use; linear threading injection technique
- Results build gradually over weeks to months, lasting approximately 2 years
- Typical protocol: ~3 sessions, ~1 month apart
- MFDS (KFDA)-approved — Made in South Korea
| 1 – 2 boxes | $131.30 / vial |
| 3 – 9 boxes | $124.74 / vial |
| 10 – 19 boxes | $118.17 / vial |
| 20 – 29 boxes | $114.23 / vial |
| 30+ boxes | Contact for quote |
What Is Olidia® PLLA 365mg — PLLA Collagen Biostimulator Lyophilized Powder?
Olidia® PLLA 365mg is a poly-L-lactic acid (PLLA) collagen biostimulator from South Korea, containing PLLA 150mg + CMC 90mg + mannitol 125mg per vial as lyophilized powder for reconstitution.
Olidia® PLLA 365mg is a poly-L-lactic acid (PLLA) collagen stimulator formulated with carboxymethylcellulose and mannitol to optimize suspension and injection. Rather than adding gel volume directly, the PLLA microparticles prompt fibroblasts to build new collagen over weeks to months, delivering natural-looking, gradual volume restoration. The correction develops progressively and the new volume is the body's own collagen. This is the same Olidia used in Korean clinics with identical composition — labeling and insert are in Korean as it is the Korean domestic-market version.
Specifications
| Product name | Olidia® PLLA 365mg |
|---|---|
| Brand | Olidia |
| Type | PLLA collagen biostimulator |
| Active ingredient | Poly-L-lactic acid (PLLA) microparticles |
| Carrier | Carboxymethylcellulose (CMC) + mannitol |
| Composition | PLLA 150mg + CMC 90mg + Mannitol 125mg = 365mg per vial |
| Presentation | 365mg × 1 vial, lyophilized powder (5ml vial) |
| Preparation | Reconstitute with ~9mL sterile water before use |
| Protocol | ~3 sessions, ~1 month apart |
| Injection depth | Deep dermis / subcutaneous (linear threading technique) |
| Mechanism | Gradual collagen biostimulation (neocollagenesis) |
| Duration | Approximately 2 years |
| Treatment areas | Facial volume restoration, nasolabial folds, marionette lines, cheek augmentation, chin, jawline |
| Origin | South Korea |
| Certification | MFDS (KFDA) |
| Storage | Store at 2–25°C. Protect from moisture. Do not freeze reconstituted suspension. |
| Shelf life | 24 months from manufacture date |
Key Benefits
- Pure L-form PLLA (poly-L-lactic acid) with 20+ years of biocompatibility research provides predictable, well-documented collagen stimulation
- Gradual neocollagenesis delivers natural-looking volume restoration that builds progressively — the result is the body's own collagen, not artificial filler
- Formulated with CMC and mannitol for optimized suspension characteristics and smooth injection
- Clinical data (NCT04568902) shows 82% volume retention at 25-month follow-up, demonstrating exceptional durability
- Versatile treatment protocol with 3 sessions ~1 month apart allows customized, progressive correction
Suggested Treatment Protocol
Olidia® PLLA 365mg is supplied as a lyophilized powder that must be reconstituted before use. Reconstitute with approximately 9mL of sterile water per the product instructions until an even suspension forms. The reconstituted suspension is injected into the deep dermis or subcutaneous layer using a linear threading technique by a licensed practitioner. A typical treatment course consists of approximately 3 sessions spaced about 1 month apart. Post-injection massage may be recommended to ensure even distribution. Results build gradually over weeks to months as new collagen forms.
Frequently Asked Questions
What is Olidia® PLLA 365mg?
Olidia® PLLA 365mg is a poly-L-lactic acid (PLLA) collagen biostimulator supplied as a 365mg lyophilized powder, reconstituted with approximately 9mL of sterile water for gradual facial volume restoration.
What is the difference between PLLA and PDLLA?
Olidia uses PLLA — the pure L-form of polylactic acid — whereas PDLLA is the amorphous D,L-form. Both stimulate collagen but differ in polymer structure and handling characteristics.
How is Olidia reconstituted?
The lyophilized powder is reconstituted with approximately 9mL of sterile water before use, per the product instructions, until an even suspension forms.
How many treatment sessions are needed?
Typically 3 sessions spaced approximately 1 month apart, depending on the treatment area and degree of correction sought.
How is it injected?
Into the deep dermis or subcutaneous layer using a linear threading technique, by a licensed practitioner.
How long do results last?
Approximately two years, as collagen is gradually stimulated and then slowly resorbed by the body.
Who can administer Olidia?
Licensed, trained practitioners only — reconstitution and linear-threading injection technique require appropriate training.
Switched to Olidia® PLLA 365mg — PLLA Collagen Biostimulator Lyophilized Powder from another brand. The reconstitute with ~9ml sterile water before use; linear threading sold me. Much better results in our practice.
Third time ordering Olidia® PLLA 365mg — PLLA Collagen Biostimulator Lyophilized Powder. The clinical data (nct04568902) shows 82% volume retention is exactly what we needed. Consistent quality every batch.
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