Dermal Fillers

Restylane® Defyne with Lidocaine — OBT™ HA Dermal Filler 1×1.0mL

4.33 (3 reviews) SKU: CYT-DF-RESTYLANE-DEFYNE
Restylane® Defyne with Lidocaine — OBT™ HA dermal filler 2×1.0mL. Designed for dynamic wrinkle correction in the nasolabial folds and marionette lines with lidocaine for comfort.
  • 20mg/ml HA with 0.3% lidocaine
  • 2x1.0mL pre-filled syringes per box
  • Needles included
  • OBT technology for dynamic correction that moves with the face
  • Designed for nasolabial folds and marionette lines
  • Duration: up to 12 months
  • Storage: 2C to 25C, do not freeze
$152.30 / box · USD
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1 - 2 boxes$152.30 / box
3 - 9 boxes$144.69 / box
10 - 19 boxes$137.07 / box
20 - 29 boxes$129.46 / box
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What Is Restylane® Defyne with Lidocaine — OBT™ HA Dermal Filler 1×1.0mL?

Restylane® Defyne with Lidocaine is a premium OBT™-based HA dermal filler from Galderma with 0.3% lidocaine for dynamic wrinkle correction in nasolabial folds and marionette lines.

Restylane® Defyne with Lidocaine utilizes Galderma's innovative OBT™ (Optimal Balance Technology) to deliver a unique gel that combines lifting capacity with flexibility for dynamic facial areas. Designed specifically for nasolabial folds and marionette lines, Defyne provides natural-looking correction that moves with the face. The inclusion of 0.3% lidocaine ensures enhanced patient comfort. Results last up to 12 months.

Specifications

Product nameRestylane Defyne with Lidocaine (Galderma)
Active ingredientCross-linked hyaluronic acid 20mg/ml + Lidocaine 3mg/ml (0.3%)
TechnologyOBT (Optimal Balance Technology)
Volume1×1.0mL pre-filled syringe per box
Needles2×27G ½" needles
Injection depthMid-dermis
DurationUp to 12 months
Treatment areasNasolabial folds marionette lines perioral area dynamic wrinkles
OriginSweden (Galderma)
CertificationCE
Storage2°C to 25°C Do not freeze
Shelf life24 months from manufacture

Key Benefits

  • OBT technology combines lift and flexibility for natural movement in dynamic areas
  • 0.3% lidocaine for enhanced patient comfort
  • Specifically designed for nasolabial folds and marionette lines
  • Gel moves naturally with facial expressions
  • Clinically proven safety from Galderma 25+ years of expertise
  • Proven longevity with results lasting up to 12 months

Suggested Treatment Protocol

Restylane Defyne should be injected into the mid-dermis using appropriate techniques such as linear threading or serial puncture. Its OBT technology allows for natural movement with facial expressions. Typical volume per session: 0.5-1.0mL per side for nasolabial folds. Touch-up evaluation at 2-4 weeks post-treatment.

For professional use only. This product is intended for purchase and administration by licensed medical or aesthetic practitioners in accordance with local regulations.

Frequently Asked Questions

What is Restylane Defyne?

Restylane Defyne with Lidocaine is an OBT-based HA dermal filler from Galderma designed for dynamic wrinkle correction in the nasolabial folds and marionette lines with 0.3% lidocaine.

What is OBT technology?

OBT (Optimal Balance Technology) is Galderma innovation that creates a gel with both lifting capacity and flexibility, allowing it to move naturally with facial expressions while providing structural support.

Does Defyne contain lidocaine?

Yes Restylane Defyne contains 0.3% lidocaine for enhanced patient comfort during injection.

How long do results last?

Results typically last 9-12 months depending on treatment area injection technique and individual factors.

What areas can Defyne treat?

Defyne is designed for nasolabial folds marionette lines and other dynamic facial areas requiring both lift and flexibility.

4.3
Based on 3 reviews
Dr. Reed
July 13, 2026

Great product range. The variety of options is very useful.

Dr. Foster
July 13, 2026

High quality dermal filler. Consistent results every time.

Dr. Evans
July 13, 2026

Excellent product for my practice. Patients are very satisfied with the results.