Skin Boosters

Profhilo — NAHYCO HA Bio-remodelling Injectable 2mL

4.50 (3 reviews) SKU: CYT-SB-PROFHILO
Profhilo 2ml — Profhilo Bio-remodelling injectable (hybrid HA). NAHYCO Bio-Remodelling · 64 mg/2ml Hybrid HA · BDDE-Free.
  • 64 mg HA per 2 mL syringe — one of the highest HA concentrations available
  • Dual molecular weight: 32 mg H-HA (1100–1400 kDa) + 32 mg L-HA (80–100 kDa)
  • NAHYCO Hybrid Technology — patented BDDE-free thermal stabilisation
  • Bio Aesthetic Points (BAP) technique — 5 points per side face or 10 on neck
  • Standard protocol: 2 sessions 4 weeks apart; maintenance ~6 months
  • Lidocaine-free, CE marked medical device from IBSA (Italy)
$143.80 / box · USD
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20 - 29 boxes$125.11 / box
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What Is Profhilo — NAHYCO HA Bio-remodelling Injectable 2mL?

Profhilo is IBSA's injectable bio-remodelling treatment with 64 mg HA per 2 mL syringe (32 mg H-HA + 32 mg L-HA), stabilised by NAHYCO Hybrid Technology without BDDE. CE marked medical device.

Profhilo is IBSA's injectable bio-remodelling treatment built on NAHYCO Hybrid Technology — one of the highest HA concentrations available at 64 mg per 2 mL syringe (32 mg high-molecular-weight H-HA + 32 mg low-molecular-weight L-HA). It is stabilised thermally without BDDE chemical cross-linkers and is used to treat skin laxity, hydration and elasticity of the face and neck. Rather than filling lines or adding volume, the hybrid cooperative complex spreads through the tissue from a small number of Bio Aesthetic Points (BAP) and slowly releases HA, stimulating collagen and elastin and improving tissue quality.

Specifications

Product nameProfhilo (H+L)
BrandProfhilo (IBSA)
Total HA64 mg per 2 mL syringe
Composition32 mg H-HA (1100–1400 kDa) + 32 mg L-HA (80–100 kDa)
TechnologyNAHYCO Hybrid Technology — BDDE-free thermal process
LidocaineNone
Presentation1 × 2 mL pre-filled syringe per box
TechniqueBio Aesthetic Points (BAP) — 5 per side face / 10 on neck
Protocol2 sessions 4 weeks apart; maintenance ~6 months
Storage2–25°C, do not freeze
CertificationCE marked medical device
OriginItaly (IBSA)

Key Benefits

  • Tightens skin laxity of face, jawline and neck
  • Improves skin elasticity and firmness
  • Delivers intense hydration for crepey or dehydrated skin
  • Stimulates collagen and elastin production
  • High spreadability for wide tissue coverage from minimal injection points

Suggested Treatment Protocol

Profhilo is administered using the Bio Aesthetic Points (BAP) technique — typically 5 points on each side of the face, or 10 points on the neck. Standard protocol: two treatments four weeks apart, with maintenance generally every six months. The high spreadability allows wide coverage from few injection sites. Must be performed by licensed practitioners using aseptic technique.

For professional use only. This product is intended for purchase and administration by licensed medical or aesthetic practitioners in accordance with local regulations.

Frequently Asked Questions

Is Profhilo a filler or a skinbooster?

Neither in the traditional sense. Profhilo opened a separate category called bio-remodelling. It is not designed to fill lines or add volume, but to remodel and tighten tissue while delivering intense hydration through a hybrid HA complex.

What is in Profhilo?

64 mg of hyaluronic acid per 2 mL syringe — 32 mg of high-molecular-weight H-HA and 32 mg of low-molecular-weight L-HA, bound by IBSA's NAHYCO thermal process. It is BDDE-free and lidocaine-free.

What does BDDE-free mean?

Most cross-linked HA gels are stabilised with the chemical agent BDDE. Profhilo instead uses a patented thermal process (NAHYCO) to stabilise the hybrid complex without chemical cross-linkers.

How is Profhilo injected?

Using the Bio Aesthetic Points (BAP) technique — typically 5 points on each side of the face, or 10 points on the neck. The high spreadability allows wide coverage from few injection sites.

How many sessions are needed?

The standard protocol is two treatments four weeks apart, with maintenance generally around every six months.

How long does it last?

Skin continues to improve over the weeks after treatment as collagen and elastin are stimulated; maintenance is commonly advised at about six months.

Which areas can be treated?

Most commonly the face, neck, décolletage and hands.

Who should administer it?

Profhilo is a CE-marked medical device for use by trained, licensed medical and aesthetic practitioners only.

4.5
Based on 3 reviews
Daniel Wang
July 18, 2026

Outstanding quality. Highly recommend for professional use.

Dr. Lisa Jackson
July 18, 2026

Top tier product. Consistent, reliable, and effective.

Tiffany Y.
April 24, 2026

What sets Profhilo — NAHYCO HA Bio-remodelling Injectable 2mL apart is the dual molecular weight: 32 mg. We've compared it side by side with competitors and this wins every time.