HELENE® HA Dermal Filler — Shine / Smooth / Mid / All
- 20mg/ml high-purity HA + 0.3% lidocaine — Micro-Bead Cross-Linking technology
- Ultra-low BDDE <2ppm and endotoxin <0.05 EU/mg for exceptional safety
- Four viscosity grades: Shine, Smooth, Mid, All (G' 250–350 Pa range)
- 1×1.0mL pre-filled syringe per unit — CE marked, ISO 13485:2016
- Made in South Korea by ACMEDI Korea — EDQM-certified raw materials
| 1 – 2 boxes | $45.60 / box |
| 3 – 9 boxes | $43.32 / box |
| 10 – 19 boxes | $41.04 / box |
| 20 – 29 boxes | $39.67 / box |
| 30+ boxes | Contact for quote |
What Is HELENE® HA Dermal Filler — Shine / Smooth / Mid / All?
HELENE® is a premium Korean hyaluronic acid dermal filler line from ACMEDI Korea, utilizing advanced Micro-Bead Cross-Linking technology with CE and EDQM-certified raw materials, achieving ultra-low BDDE residue (<2ppm) and exceptional biocompatibility.
HELENE® represents ACMEDI Korea's advanced approach to hyaluronic acid dermal filler technology, employing a proprietary Micro-Bead Cross-Linking process that creates a stable, monophasic HA gel with superior rheological properties. The manufacturing process achieves ultra-low BDDE residue (<2ppm) and endotoxin levels (<0.05 EU/mg), significantly exceeding international safety standards. Each variant is formulated at 20mg/ml HA concentration with 0.3% lidocaine for enhanced patient comfort, supplied in 1×1.0mL pre-filled syringes. With a G' (elastic modulus) range of 250–350 Pa across the four viscosity grades, the HELENE range covers the full clinical spectrum — from superficial hydration and fine line correction (Shine) through to deep structural volumizing and facial contouring (All). CE marked and ISO 13485:2016 certified for international clinical use.
Specifications
| Product name | HELENE® HA Dermal Filler (ACMEDI Korea) |
|---|---|
| Active ingredient | Cross-linked hyaluronic acid 20mg/ml (Micro-Bead Cross-Linking) + Lidocaine 0.3% |
| Volume | 1×1.0mL pre-filled syringe per unit |
| Application | Professional injectable dermal filler for licensed practitioners |
| Treatment areas | Shine: fine lines, hydration / Smooth: moderate NLF, lips / Mid: deep folds, chin / All: cheeks, temples, structural contouring |
| Origin | South Korea (ACMEDI Korea) |
| Storage | 2–25°C. Do not freeze. Store away from direct sunlight. |
| Shelf life | 24 months from manufacture date |
Key Benefits
- Advanced Micro-Bead Cross-Linking technology creates a stable monophasic HA gel with consistent rheological properties for predictable clinical outcomes
- Ultra-low residual BDDE (<2ppm) and endotoxin (<0.05 EU/mg) minimize the risk of inflammatory reactions and ensure exceptional biocompatibility
- Four distinct viscosity grades cover the full treatment spectrum from superficial hydration to deep structural volumizing within a single brand portfolio
- Pre-mixed 0.3% lidocaine enhances patient comfort throughout the injection procedure across all variants
- CE marked and ISO 13485:2016 certified — complies with international quality and safety standards for clinical use in EU and global markets
Suggested Treatment Protocol
Treatment planning and injection depth depend on the chosen variant. HELENE Shine is injected into the superficial dermis for fine line correction and hydration. HELENE Smooth targets the mid-dermis for moderate wrinkle correction. HELENE Mid is placed in the deep dermis for pronounced folds and localized volume. HELENE All is injected into the deep subcutaneous or supraperiosteal plane for structural volume restoration and contouring. A thorough patient assessment and touch-up sessions may be scheduled as determined by the treating practitioner.
Frequently Asked Questions
What is HELENE®?
HELENE® is a premium Korean hyaluronic acid dermal filler range from ACMEDI Korea, utilizing advanced Micro-Bead Cross-Linking technology with CE and EDQM-certified raw materials, achieving ultra-low BDDE residue (<2ppm) for exceptional safety.
What is the difference between Shine, Smooth, Mid and All?
Shine (lowest viscosity) targets superficial fine lines and hydration; Smooth (medium) treats moderate nasolabial folds and lips; Mid (higher G') addresses deep folds and chin contouring; All (highest G' up to 350 Pa) provides structural volumizing for cheeks, temples and full facial contouring.
What is the HA concentration in HELENE®?
All four variants contain 20mg/ml of cross-linked hyaluronic acid with 0.3% lidocaine, supplied in 1×1.0mL pre-filled syringes. The difference between variants lies in cross-linking density and G' (elastic modulus).
What is Micro-Bead Cross-Linking technology?
Micro-Bead Cross-Linking is ACMEDI Korea's proprietary technology that creates a stable, monophasic HA gel with controlled particle size distribution. This process achieves ultra-low BDDE residue (<2ppm) and endotoxin levels (<0.05 EU/mg), ensuring exceptional purity and biocompatibility.
How should HELENE® be stored?
Store at 2–25°C away from direct sunlight. Do not freeze. Shelf life is 24 months from the manufacture date. Use immediately after opening the sterile package.
What certifications does HELENE® hold?
HELENE® is CE marked for European and international markets, ISO 13485:2016 certified for quality management, and uses EDQM-certified raw materials. It is manufactured by ACMEDI Korea under strict GMP conditions.
Do you offer wholesale pricing on HELENE®?
Yes. Cytollia supplies HELENE® at tiered wholesale prices for licensed clinics and distributors, with volume discounts on larger orders. All four variants are priced identically at $45.60 per box.
Top tier product. Consistent, reliable, and effective.
Brilliant product. Exceeds expectations consistently.
What sets HELENE® HA Dermal Filler — Shine / Smooth / Mid / All apart is the ultra-low bdde <2ppm and endotoxin <0.05 eu/mg for exceptional safety. We've compared it side by side with competitors and this wins every time.
Our practitioners love working with HELENE® HA Dermal Filler — Shine / Smooth / Mid / All. The 20mg/ml high-purity ha + 0.3% lidocaine — makes it predictable and easy to dose.
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