Ellanse M — PCL Collagen-Stimulating Dermal Filler 2×1mL
- 30% PCL microspheres + 70% CMC gel carrier — STAT Technology
- 2×1mL pre-filled syringes per box, with 4×27G ¾" needles
- Dual-phase: immediate correction (CMC) + sustained collagen stimulation (PCL) ~2 years
- Particle size 25-50μm for controlled neocollagenesis
- CE Mark (Class III medical device), ISO 13485:2016 — For licensed professionals only
| 1 – 2 boxes | $418.80 / box |
| 3 – 9 boxes | $397.86 / box |
| 10 – 19 boxes | $376.92 / box |
| 20 – 29 boxes | $364.36 / box |
| 30+ boxes | Contact for quote |
What Is Ellanse M — PCL Collagen-Stimulating Dermal Filler 2×1mL?
Ellansé M is the mid-duration tier in Sinclair Pharma's STAT (Sustained And Tunable) Technology biostimulator range, containing 30% PCL microspheres in a 70% CMC gel carrier for immediate volume correction with sustained collagen stimulation lasting approximately 2 years.
Ellansé M by Sinclair (Aesthetics, UK) is the mid-duration tier of the four-tier PCL biostimulator system, engineered around STAT Technology (Sustained And Tunable). Unlike hyaluronic acid fillers that replace volume with HA gel, Ellansé M triggers the body's own collagen production (neocollagenesis) for results lasting approximately 2 years — 3x longer than conventional HA fillers. The two-phase mechanism delivers immediate correction via the CMC gel carrier (Phase 1, 0-3 months), while the 25-50μm PCL microspheres stimulate sustained Type I collagen formation around each microsphere (Phase 2, 3 months-2 years). The fully bioresorbable PCL microspheres are replaced by native collagen, producing durable structural support the body recognizes as its own tissue. Choose Ellansé M for moderate-to-deep facial correction requiring long-term, naturally regenerated structure.
Specifications
| Product name | Ellanse M (Sinclair Aesthetics, UK) |
|---|---|
| Type | PCL collagen-stimulating biostimulator filler — Mid-duration tier |
| Technology | STAT (Sustained And Tunable) Technology |
| Active ingredient | 30% Polycaprolactone (PCL) microspheres (25-50μm) + 70% Carboxymethylcellulose (CMC) gel carrier |
| Volume | 2 × 1mL pre-filled syringes per box |
| Needles | 4 × 27G ¾" needles per box |
| Injection depth | Mid-to-deep dermis |
| Mechanism | Dual-phase: Phase 1 (0-3mo) CMC gel immediate correction / Phase 2 (3mo-2yr) PCL-stimulated neocollagenesis |
| Duration | ~2 years (18-24 months) |
| Treatment areas | Nasolabial folds, marionette lines, cheek enhancement, chin projection, jawline contour, temple volumizing |
| Origin | United Kingdom (Sinclair Aesthetics, part of Huadong Medicine) |
| Certification | CE Mark (Class III medical device), ISO 13485:2016 — Distributed in 60+ countries |
| Storage | 2-25°C. Do not freeze. Protect from light. |
| Shelf life | 36 months unopened |
Key Benefits
- Dual-phase STAT Technology delivers visible results from Day 1 while stimulating native collagen for approximately 2 years of sustained improvement
- 3x longer duration than HA fillers reduces the frequency of maintenance treatments, offering superior cost-effectiveness for patients
- PCL microspheres (25-50μm) trigger controlled Type I collagen formation that the body recognizes as native tissue, producing natural-looking structural support
- Fully bioresorbable through hydrolysis — no permanent implant remains, with CMC metabolized and PCL microspheres resorbed over the product lifecycle
- Versatile mid-deep dermal application suitable for nasolabial folds, marionette lines, cheek enhancement, chin projection, jawline contour and temple volumizing
Suggested Treatment Protocol
Ellansé M is injected into the mid-to-deep dermis using a 27G ¾" needle with linear threading technique, depositing 0.05-0.1mL per pass. Maximum 2mL per treatment session. A 5-minute circular post-treatment massage is recommended to ensure even distribution of the PCL microspheres. Treatment planning should account for the dual-phase mechanism — the immediate CMC fill provides visible correction from Day 1, while the collagen stimulation phase (3-24 months) progressively restores native tissue structure. Touch-up sessions may be scheduled at the treating practitioner's discretion.
Frequently Asked Questions
What is Ellansé M?
Ellansé M is the mid-duration tier of Sinclair Pharma's STAT Technology PCL biostimulator range. It contains 30% Polycaprolactone (PCL) microspheres (25-50μm) in a CMC gel carrier, providing immediate volume correction while stimulating sustained collagen production for approximately 2 years.
How is Ellansé M different from Ellansé S?
Both contain 30% PCL + 70% CMC, but Ellansé M is engineered for longer duration (~2 years vs S: 12+ months) through optimized PCL microsphere characteristics. M is suited for moderate-to-deep facial correction requiring sustained structural support.
How does STAT Technology work?
STAT (Sustained And Tunable) Technology delivers a dual-phase mechanism: Phase 1 (0-3 months) the CMC gel carrier provides immediate volume correction visible from Day 1. Phase 2 (3 months-2 years) the PCL microspheres stimulate Type I collagen formation around each microsphere. As CMC is metabolized and PCL microspheres bioresorb, native collagen replaces the volume seamlessly.
How long do results last?
Clinical data shows results lasting approximately 2 years (18-24 months) for Ellansé M — approximately 3x longer than conventional HA fillers. Individual results may vary based on skin type, age, metabolic factors, and treatment area.
Which areas can be treated with Ellansé M?
Ellansé M is indicated for moderate-to-deep dermal correction including nasolabial folds, marionette lines, cheek enhancement, chin projection, jawline contouring, and temple volumizing.
Is Ellansé M safe?
Ellansé M is a CE Marked Class III medical device manufactured under ISO 13485:2016 standards, distributed in 60+ countries. PCL is a biocompatible, fully bioresorbable material with an established safety profile in medical devices. Treatment should only be performed by qualified medical professionals.
Happy with the purchase. Everything was as described and delivery was prompt.
Third time ordering Ellanse M — PCL Collagen-Stimulating Dermal Filler 2×1mL. The 30% pcl microspheres + 70% cmc gel carrier — stat is exactly what we needed. Consistent quality every batch.
Used Ellanse M — PCL Collagen-Stimulating Dermal Filler 2×1mL on several patients last month. The 30% pcl microspheres + 70% cmc gel carrier — stat performs as described. Will keep ordering.
Great product overall. The ellansé m is the mid-duration tier in sinclair is a standout feature. Already recommended it to two colleagues.
Great product overall. The 30% pcl microspheres + 70% cmc gel carrier — stat is a standout feature. Already recommended it to two colleagues.
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