Coretox 100U — Botulinum Toxin Type A (100 Units/Vial)
- 100 units of 150 kDa botulinum toxin type A per vial — lyophilized (freeze-dried) powder
- Complexing-protein-free formulation — essentially pure neurotoxin, minimizing protein load
- Non-animal-derived; formulated without human serum albumin (polysorbate 20, sodium chloride, L-methionine)
- Clinically equivalent efficacy and safety to an established reference neurotoxin (Ona-BoNTA) in moderate-to-severe glabellar lines
- Standard dilution: 2.5 mL preservative-free 0.9% saline per 100 U → 4 U / 0.1 mL
- Use within 24 hours after reconstitution at 2–8°C; cold-chain required
- Origin: South Korea; regulated professional product for licensed healthcare professionals only
| 1 – 2 boxes | $40.50 / box |
| 3 – 9 boxes | $38.48 / box |
| 10 – 19 boxes | $36.45 / box |
| 20 – 29 boxes | $35.24 / box |
| 30+ boxes | Contact for quote |
What Is Coretox 100U — Botulinum Toxin Type A (100 Units/Vial)?
A high-purity 150 kDa botulinum toxin type A complex (100 units per vial) supplied as a lyophilized powder for professional injection. It is formulated as a complexing-protein-free, non-animal-derived neurotoxin that temporarily relaxes targeted muscles by blocking acetylcholine release, improving moderate-to-severe glabellar lines in adult patients.
Coretox 100U is a high-purity 150 kDa botulinum toxin type A supplied as a lyophilized white powder in a transparent glass vial. It is the first botulinum toxin of its kind to be produced without animal-derived components in the toxin culture, and it is formulated without human serum albumin — using polysorbate 20, sodium chloride and L-methionine as excipients instead. Complexing proteins are removed during purification, so the vial delivers essentially pure neurotoxin, minimizing the protein load delivered to the patient and reducing immunogenicity risk. Following injection, the toxin binds to motor nerve terminals and cleaves SNAP-25, blocking acetylcholine release so the treated muscle relaxes and dynamic wrinkles become visibly shallower. Clinical studies demonstrate comparable efficacy and safety to an established reference neurotoxin in patients with moderate-to-severe glabellar lines. Cold-chain shipping (2–8°C) is required from manufacturer to clinic. Supplied to licensed healthcare professionals only.
Specifications
| Product name | Coretox 100U |
|---|---|
| Product type | Botulinum toxin type A neurotoxin complex — lyophilized powder for injection |
| Active ingredient | Clostridium botulinum toxin type A (150 kDa, Hall strain), 100 units per vial |
| Presentation | 1 vial × 100 units per box (lyophilized powder) |
| Purity | High-purity 150 kDa neurotoxin, complexing-protein-free |
| Excipients | Polysorbate 20, sodium chloride, L-methionine (no human serum albumin, no animal-derived components) |
| Mechanism of action | Cleaves SNAP-25, blocking acetylcholine release at the neuromuscular junction and temporarily relaxing treated muscles |
| Indication | Temporary improvement of moderate-to-severe glabellar lines in adult patients aged 20–65 |
| Treatment areas | Glabellar lines, forehead lines, crow's feet, masseter contouring, upper limb spasticity (therapeutic) |
| Onset of action | 2–7 days (typical clinical range) |
| Duration of effect | 4–6 months (dose- and area-dependent) |
| Reconstitution | Preservative-free 0.9% sodium chloride (2.5 mL per 100 U → 4 U / 0.1 mL) |
| Storage | 2–8°C, protected from light; do not freeze (cold-chain required) |
| Shelf life | 36 months (unopened) |
| Use after reconstitution | Within 24 hours at 2–8°C |
| Origin | South Korea |
Key Benefits
- 150 kDa pure-neurotoxin formulation — complexing proteins removed to reduce protein load
- Non-animal-derived, HSA-free formulation supports tolerability for sensitive patients
- Low immunogenicity risk supports repeated treatment sessions
- Clinically equivalent efficacy and safety to an established reference neurotoxin
- Versatile: glabellar lines, forehead lines, crow's feet, masseter contouring and more
- Reliable, predictable muscle relaxation for natural-looking results that preserve facial expression
Suggested Treatment Protocol
For professional use only. Reconstitute with preservative-free 0.9% sodium chloride (standard: 2.5 mL per 100 U vial, yielding 4 U per 0.1 mL). Inject the saline slowly down the inner vial wall — do not shake — and gently swirl until the powder is fully dissolved. The solution should be clear and free of particles; use within 24 hours when stored at 2–8°C. Glabellar lines: 20 U total — 0.1 mL (4 U) at each of five points (two per corrugator muscle and one in the procerus muscle), using a 30-gauge needle. Forehead lines: 10–20 U across 4–6 injection points. Crow's feet: 12–15 U per side across 3 injection points. Masseter contouring and therapeutic dosing follow individual clinical protocols. Avoid diffusion into the levator palpebrae superioris and zygomaticus major. Contraindicated in patients with hypersensitivity to any component, neuromuscular disorders, and during pregnancy or lactation. Avoid concomitant use of aminoglycosides or agents interfering with neuromuscular transmission.
Frequently Asked Questions
What is Coretox 100U?
Coretox 100U is a high-purity 150 kDa botulinum toxin type A (100 units per vial) supplied as a lyophilized powder. It is formulated as a complexing-protein-free, non-animal-derived neurotoxin that temporarily relaxes treated muscles by blocking acetylcholine release.
How is Coretox different from other botulinum toxin type A products?
Coretox is produced without animal-derived components in the toxin culture and is formulated without human serum albumin. Complexing proteins are removed during purification, so each vial delivers essentially pure 150 kDa neurotoxin, minimizing the protein load and immunogenicity risk.
How is Coretox 100U reconstituted?
Reconstitute with preservative-free 0.9% sodium chloride — the standard dilution for a 100 U vial is 2.5 mL, yielding 4 U per 0.1 mL. Inject the saline slowly down the inner vial wall, do not shake, and gently swirl until fully dissolved. Use within 24 hours when stored at 2–8°C.
When do results appear and how long do they last?
Onset of action typically occurs within 2–7 days, with the full effect visible around 2 weeks. Results usually last 4–6 months depending on the treated area, dosage and individual metabolism.
Is Coretox clinically validated?
Yes. Clinical studies demonstrate comparable efficacy and safety to an established reference neurotoxin (Ona-BoNTA) in patients with moderate-to-severe glabellar lines, supporting its use as an effective alternative.
Do you offer wholesale pricing?
Yes. Volume discounts apply: 3–9 boxes 5% off, 10–19 boxes 10% off, 20–29 boxes 13% off, and 30+ boxes contact us for a quote.
Coretox 100U reconstituted easily with 2.5 mL saline and the 150 kDa pure-neurotoxin formulation is a standout for patients with sensitivities. My glabellar-line patients saw results within the expected window and appreciated the protein-free profile.
Using the 100-unit vial for forehead and crow's feet work. The protein-free, non-animal-derived formulation is reassuring for repeat patients, results held for several months, and the cold-chain packaging arrived intact. A strong alternative to my other botulinum toxin type A products.
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