If you are looking at the P198 range and wondering which product actually fits your goal, the answer is refreshingly simple: choose SB Plus for tired, dehydrated or uneven-looking skin, and HB Plus when the concern is the scalp, shedding or thinning hair. The Activating Solution is the companion formula that completes the professional Program.
That clear split is what makes P198 easy to understand. It is not one vague exosome product trying to solve every beauty concern; it gives skin and hair their own focused route, with benefits a client can recognise in the mirror.
Skin, hair or companion solution
Start here: choose by the result you want
| If the client wants… | Choose… | The result to focus on |
|---|---|---|
| More glow, hydration and smoother-looking skin | P198 Filcore SB Plus Program | Fresher radiance, softer texture, improved elasticity, less obvious pores and fine lines, and a more even-looking complexion |
| A healthier scalp and stronger, fuller-looking hair | P198 Filcore HB Plus Program | Better scalp condition, follicle support, reduced appearance of shedding and improved hair vitality, strength and density |
| The companion solution for the P198 professional system | P198 Activating Solution | Hydrating and conditioning support from a blend that includes hyaluronic acid, amino acids and vitamins in reviewed Primoris material |
The choice should begin with the concern, not with technical terminology. A client who says “my skin looks flat and rough” belongs in the SB Plus conversation; someone worried about a stressed scalp, extra shedding or visibly thinner hair belongs in the HB Plus conversation.
One family with two clear jobs
Why P198 feels more considered than a one-product exosome range
Exosomes are tiny extracellular vesicles involved in communication between cells. Their beauty appeal comes from a wider research story around skin renewal, hydration, collagen and elastin support, recovery and follicle activity. P198 turns that broad idea into two products with very different jobs.
SB Plus keeps the conversation on visible skin quality. HB Plus moves it to the scalp and the environment around the hair follicle. For a clinic, that distinction matters because a glow treatment and a hair-density treatment should never sound like the same service with a different name.
The range also uses a lyophilised format that keeps the core material separate until the professional Program is prepared. Paired with the Activating Solution, it creates a complete treatment story: a focused exosome product for the main concern, followed by complementary hydration and conditioning support.
Glow, hydration and smoother skin
SB Plus is the skin-quality route
P198 Filcore SB Plus is for clients who want their own features to look fresher rather than fuller. It does not aim to change facial shape in the way a dermal filler does; the value is in better-looking skin—more light, more smoothness and a healthier overall finish. Cytollia’s skin booster vs filler guide explains that distinction in more detail.
When skin looks flat or dehydrated
Dehydrated skin does not reflect light evenly, so it can look dull even when there is no major pigmentation problem. SB Plus puts hydration and radiance at the centre of the result. The goal is skin that looks plumper, calmer and naturally luminous, without relying on heavy makeup to create the glow.
When texture and pores are the bigger concern
Rough texture catches the light in all the wrong places and makes pores appear more obvious. A strong SB Plus result is not a filtered, poreless face; it is a smoother surface with softer pore contrast and a cleaner, more polished finish in natural light.
When early lines and uneven tone are starting to show
As skin becomes drier and less elastic, fine lines can look sharper and the complexion can appear less even. SB Plus fits clients who want to soften that tired look by improving elasticity, moisture and overall tone at the same time. It is especially appealing when no single concern is severe, but the face no longer looks as rested as it used to.
The changes clients can actually see
What a good SB Plus result actually looks like
The first change worth watching is the finish of the skin. Better hydration can make the face look fresher and more reflective, while makeup may sit more smoothly over areas that previously looked dry or textured.
The next layer is skin quality. Texture should look more refined, pores less visually dominant and early lines softer. With consistent photography, improvements in elasticity and tone also become easier to see than they are in a bathroom mirror from day to day.
These are not random marketing categories. A 2026 systematic review covering 19 human studies of exosome-based skin interventions reported improvements across hydration, elasticity, wrinkles, pores, pigmentation and overall appearance. Those findings support the endpoints clinics already use to assess an SB Plus Program: glow, smoothness, resilience and a more even complexion.
The scalp and hair route
HB Plus is the answer when the concern is hair
P198 Filcore HB Plus earns its place as a separate product because scalp and hair concerns need a different goal from facial rejuvenation. A client worried about shedding is not simply asking for a moisturised scalp; they want to protect the quality of the hair they have and support the environment in which new hair grows.
HB Plus is therefore built around three connected improvements: a healthier scalp, stronger follicle support and better visible hair quality. It suits conversations about dryness or sensitivity at the scalp, weakened strands, increased shedding, early thinning and hair that has lost its usual strength or fullness.
In practical terms, the desired result is a scalp that feels more balanced and hair that looks stronger, denser and more vital. That is a much more useful promise to discuss than a generic “regenerative” label because it gives both the client and the clinic something visible to follow.
Why HB Plus exists as its own product
Can P198 HB Plus help hair growth?
Yes—hair-growth support is central to the reason HB Plus exists. It is the scalp-and-hair product in the P198 family, developed to improve the environment around the follicle, support follicle vitality and help weakened or thinning hair regain strength, density and a fuller appearance.
Primoris cites an ex vivo test using human scalp-derived hair follicles. In that laboratory model, the tested exosome material was associated with support for follicle length, maintenance of root diameter and a lower proportion of follicles entering the catagen, or regression, phase. Put into normal language, the product-development logic is about helping follicles remain active and supporting healthier hair growth—not merely making the scalp feel conditioned.
The wider 2026 trichology literature also describes encouraging exosome-related findings for hair density, thickness and scalp health. For a client, the most meaningful signs are a better shedding trend, a healthier-looking scalp, stronger strands and gradual improvement in the appearance of the part line or other thinning areas. Those are the outcomes worth photographing and reviewing consistently through the professional Program.
The support layer in the Program
What the Activating Solution brings to the Program
The Activating Solution is the support layer that helps the P198 Program feel complete. Reviewed Primoris material describes a blend containing hyaluronic acid, amino acids, vitamins, peptides and antioxidants—ingredients that fit naturally with hydration, conditioning and recovery-focused care.
With SB Plus, that supporting blend complements the glow, moisture and smoothness story. With HB Plus, it supports scalp conditioning and a healthier environment around the hair. Cytollia’s current SB Plus and HB Plus Program pages include the paired solution, while the separate P198 Activating Solution page gives clinics a direct route when checking the companion product.
Choose the right product conversation
P198, ASCE or Rejuran: which conversation are you having?
These names are often compared because they all appear in skin-quality discussions, but they are not interchangeable.
| Option | What it is | The conversation it suits best |
|---|---|---|
| P198 SB Plus | A skin-focused exosome Program | Glow, hydration, texture, pores, elasticity, fine lines, tone and recovery |
| P198 HB Plus | A dedicated scalp-and-hair exosome Program | Scalp condition, follicle vitality, shedding, strength, density and fuller-looking hair |
| ASCE | A separate professional exosome platform with its own formulations | Clinics already comparing exosome brands and selecting a specific skin or hair protocol |
| Rejuran | A polynucleotide-based skin-quality product | Clients or clinics specifically looking for a PN-centred approach to skin renewal |
P198’s strongest point is the clean division between skin and hair within one family. ASCE is a brand-to-brand exosome comparison, while Rejuran starts from a different ingredient category altogether. For a fuller explanation of that category difference, see Cytollia’s PDRN vs Exosomes guide.
Clear benefits make consultation easier
Why P198 makes sense on a clinic menu
P198 gives a clinic an advanced product story without forcing the client to understand laboratory vocabulary before they can see the value. The consultation can begin with a familiar concern—dull skin, rough texture, visible thinning or increased shedding—and move directly to the relevant product.
It also gives the clinic two clear service directions under one recognisable Korean professional range. SB Plus can sit inside a skin-quality and recovery menu, while HB Plus gives hair and scalp clients a dedicated regenerative option rather than an adapted facial treatment.
Most importantly, both routes lead to results that can be followed. Radiance, texture, pores and tone can be photographed for SB Plus; scalp condition, shedding trend, part-line width and hair quality can be followed for HB Plus. That makes the treatment easier to explain before it begins and easier to value when the client returns.
Straight answers before choosing
Questions people ask before choosing P198
What does P198 ExoHealer SB Plus do?
SB Plus targets visible skin quality. Its main goals are stronger hydration, more radiance, smoother texture, improved elasticity, softer-looking fine lines, less obvious pores and a more even complexion.
Who is SB Plus best for?
It is a natural fit for skin that looks dull, dry, rough, tired or uneven, especially when the client wants an overall rejuvenated finish rather than added facial volume.
Is P198 SB Plus a filler?
No. SB Plus belongs in a skin-quality conversation, not a facial-shaping one. It focuses on the condition and appearance of the skin rather than creating projection or replacing volume.
What does P198 ExoHealer HB Plus do?
HB Plus focuses on the scalp, follicles and visible hair quality. It is used to support a healthier scalp environment, reduce the appearance of shedding, strengthen weakened hair and improve vitality, density and fullness.
Can HB Plus help with hair growth?
Yes. HB Plus is specifically developed as the hair-growth-support route in the P198 range. Manufacturer follicle-model data and the wider exosome literature support its focus on follicle activity, density, thickness and scalp health.
How soon do P198 results show?
With SB Plus, hydration and glow are the first changes to watch, followed by texture, elasticity and tone. With HB Plus, scalp comfort and hair quality are easier to notice first, while shedding and density are better judged through consistent follow-up images over the Program.
Is the Activating Solution included with SB Plus and HB Plus?
The current Cytollia SB Plus and HB Plus Program listings include their paired Activating Solution, so each route is presented as a complete professional Program.
How is P198 different from ASCE and Rejuran?
P198 stands out by offering separate SB skin and HB hair products inside one exosome family. ASCE is another exosome platform, while Rejuran is based on polynucleotides rather than exosomes.
Where can clinics buy P198 ExoHealer?
Cytollia currently lists SB Plus, HB Plus and the Activating Solution. Clinics can also contact Cytollia when they need help choosing the right P198 route.
Choose by the result that matters
The simple way to choose
Choose SB Plus when the desired change is visible in the skin: more glow, better hydration, smoother texture, softer fine lines and a more even finish. Choose HB Plus when the concern begins at the scalp and shows up as shedding, weakness or thinning hair. The Activating Solution completes the corresponding professional Program with complementary hydration and conditioning support.
P198 works because the product choice follows the result the client actually wants. Skin has its route, hair has its route, and neither needs to be buried under a catalogue-style explanation.
Current Cytollia product routes
Shop P198 at Cytollia
GLOW · HYDRATION · TEXTURE
P198 Filcore SB Plus Program
For skin that should look brighter, smoother, more hydrated and more refreshed
View SB Plus →
SCALP · FOLLICLES · HAIR GROWTH
P198 Filcore HB Plus Program
For scalp renewal, follicle support and stronger, denser, fuller-looking hair
View HB Plus →
HYDRATION · CONDITIONING · SUPPORT
P198 Activating Solution
The companion solution that completes the professional P198 system
View the Activator →
MORE SKIN-QUALITY OPTIONS
Skin Boosters
Explore professional products for hydration, radiance and visible skin renewal
Browse the category →
EXOSOMES OR POLYNUCLEOTIDES
PDRN vs Exosomes
See how the two regenerative categories differ before choosing a product route
Read the guide →
PRODUCT HELP
Ask Cytollia
Get help matching the P198 range to your clinic’s skin or hair offering
Contact Cytollia →
Evidence and disclosure
Sources and editorial disclosure
- P198 ExoHealer official product directory
- P198 official Filcore SB Plus Program page
- P198 official Filcore HB Plus Program page
- P198 official Filcore Activating Solution page
- Primoris International medical-aesthetic company profile
- Primoris 2024 product leaflet with skin and hair test summaries
- Efficacy of Exosome-Based Therapies for Skin Rejuvenation: A Systematic Review of Human Studies
- Exosomes in Trichology: A Literature Review
- MISEV2023 guidance for extracellular-vesicle research
This article supports product education and professional purchasing. Benefits can vary with the client, professional Program and product version. Follow the current manufacturer documentation and applicable local requirements for professional use.
