Elravie Re2O Fine (3 mL Syringe / 50 mg)
- 50 mg freeze-dried hADM per syringe — fine-particle human ECM booster
- Mean particle size about 50 µm — the finer cut versus standard Re2O (150 mg, ~75 µm)
- Supplies ECM structure (collagens, elastin, GAGs, laminin, fibronectin), not HA volume
- Positioned for thin skin — periorbital area, perioral lines and neck
- No carboxymethyl cellulose, no lidocaine; no stated HA concentration in the syringe
- 3 mL is the syringe capacity — freeze-dried tissue, reconstitute per the IFU
| 1 - 4 boxes | $234.80 / box |
| 5 - 9 boxes | $225.41 / box |
| 10 - 19 boxes | $216.02 / box |
| 20+ boxes | $211.32 / box |
What Is Elravie Re2O Fine (3 mL Syringe / 50 mg)?
Elravie Re2O Fine is the fine-particle version of the Re2O human ECM skin booster: 50 mg of freeze-dried human acellular dermal matrix (hADM) in one 3 mL-capacity syringe, with particles averaging about 50 µm. It delivers extracellular matrix structure rather than hyaluronic acid volume, and is positioned for thin skin — the periorbital area, perioral lines and the neck.
Elravie Re2O Fine belongs to a different family from HA boosters. Instead of adding water-binding gel or signalling the skin to rebuild collagen, it places processed human dermal matrix — collagen, elastin, glycosaminoglycans and other structural proteins — directly into the dermis, where it is intended to integrate with the skin's own scaffold. The matrix is decellularised without surfactants, screened with nucleic-acid testing and gamma irradiated, then micro-ground: Fine is the smaller cut, with a mean particle size of about 50 µm at 50 mg, against roughly 75 µm and 150 mg for the standard Re2O syringe. Because the particles are finer, the product is aimed at thin, delicate areas where a coarser suspension is harder to distribute evenly. The pack is freeze-dried tissue in a 3 mL-capacity syringe — the 3 mL refers to the container, not to a ready-to-inject volume of gel. It contains no carboxymethyl cellulose and no lidocaine, and no hyaluronic acid concentration is stated for the syringe. Reconstitution follows the IFU in the box and is done immediately before use by the treating professional.
Specifications
| Product name | Elravie Re2O Fine (3 mL Syringe / 50 mg) |
|---|---|
| Brand | Elravie (South Korea) |
| Type | Human ECM skin booster — fine-particle hADM |
| Active ingredient | 50 mg freeze-dried human acellular dermal matrix (hADM) per syringe |
| Particle size | Mean about 50 µm (fine cut) |
| ECM composition | Collagen types I, III, IV, V, VI, VII, XVII with elastin, glycosaminoglycans, laminin and fibronectin |
| Format | 1 × 3 mL-capacity syringe — freeze-dried tissue; 3 mL is container capacity, not liquid volume |
| Reconstitution | Reconstitute immediately before use — follow the IFU supplied in the box |
| Additives | No carboxymethyl cellulose, no lidocaine, no stated HA concentration |
| Processing | Surfactant-free decellularisation; nucleic-acid donor screening; gamma irradiation (SAL 10⁻⁶) |
| Injection plane | Thin-skin placement determined by the treating professional |
| Needle | Needle or cannula per the IFU and practitioner technique |
| Course | No session count stated by the manufacturer — Korean clinics commonly plan 3 sessions about 4 weeks apart; confirm against the IFU |
| Reversibility | Not a cross-linked HA product — not reversed with hyaluronidase |
| Treatment areas | Periorbital thin skin, perioral lines, neck; skin texture, firmness and hydration |
| Origin | South Korea |
| Certification | Human-tissue product (Korea); Thai FDA Class 4 medical device approval (2026) |
| Storage | Unopened packs listed at 1–30°C — follow the temperature printed on the carton |
| Shelf life | As printed on the carton |
Key Benefits
- Places human-derived extracellular matrix directly into the dermis rather than only hydrating or signalling
- Retains multiple collagen types (I, III, IV, V, VI, VII, XVII) together with elastin, glycosaminoglycans, laminin and fibronectin — an intact matrix, not a blended collagen shot
- Finer particle cut (about 50 µm) is intended for thin, delicate areas where coarser material is harder to place evenly
- Surfactant-free decellularisation, nucleic-acid donor screening and gamma irradiation to a 10⁻⁶ sterility assurance level, per company materials
- No cross-linked HA, no CMC and no lidocaine in the syringe — suitability is judged on tissue matrix, not on gel volume
Suggested Treatment Protocol
Elravie Re2O Fine is supplied as freeze-dried hADM in a 3 mL-capacity syringe and must be reconstituted immediately before use according to the IFU in the box — it is not a ready-to-inject gel. The reconstituted suspension is placed into the dermis of thin areas (periorbital, perioral, neck) by a licensed professional, typically by microdroplet or cannula technique; it is not intended as a volumising bolus. Session planning follows the IFU — no fixed number of sessions is stated by the manufacturer, and Korean clinics commonly plan three sessions about four weeks apart. The product is single-use and must not be shared between patients. Store unopened packs at the temperature printed on the carton, and discard any unused reconstituted material.
Frequently Asked Questions
What is Elravie Re2O Fine?
It is the fine-particle version of the Re2O human ECM skin booster: 50 mg of freeze-dried human acellular dermal matrix (hADM) with a mean particle size of about 50 µm, supplied in one 3 mL-capacity syringe for placement into thin skin by a licensed professional.
Is the 3 mL syringe 3 mL of gel?
No. The 3 mL figure is the capacity of the syringe. The contents are 50 mg of freeze-dried tissue, which is reconstituted before use — it is not 3 mL of ready-to-inject gel and not a 50 mg/mL solution.
How is Re2O Fine different from standard Re2O 150 mg?
Standard Re2O carries 150 mg with a mean particle size of roughly 75 µm; Re2O Fine carries 50 mg with a mean of about 50 µm. The finer cut is intended for thin, delicate areas. The two packs are not interchangeable.
Is Re2O Fine a hyaluronic acid filler?
No. It is a human tissue-derived extracellular matrix product, not a cross-linked HA filler. It contains no carboxymethyl cellulose and no lidocaine, and no HA concentration is stated for the syringe. Because it is not HA, it is not reversed with hyaluronidase.
Which areas is it used for?
Launch positioning describes thin skin — the periorbital area, perioral lines and the neck — for skin texture, firmness and hydration. The manufacturer's stated purpose is structural reconstruction and functional recovery of damaged or deficient skin. Suitability for an individual patient is a clinical decision.
How many sessions are needed?
No session count is published on the manufacturer's product page. Korean clinics commonly plan three sessions about four weeks apart, which is clinical practice rather than a manufacturer instruction — confirm the schedule against the IFU.
How should it be stored?
Distributors list unopened packs at 1–30°C; follow the storage temperature and expiry printed on the carton. Reconstitute immediately before use and discard any unused reconstituted material.
Do you offer wholesale pricing on Elravie Re2O Fine?
Yes. Cytollia supplies Elravie Re2O Fine at tiered wholesale prices for licensed clinics and distributors, with volume discounts on larger orders.
Product arrived in good condition and the documentation was complete. Dispatch took two days longer than the estimate, so four stars rather than five — no complaint about the material itself.
What I like is that it is matrix rather than another HA gel — different behaviour in thin skin, and no lidocaine to complicate the history check. Bag-free packaging is compact for storage too.
Ordered two boxes for a perioral and neck plan. Carton and IFU were in the box as expected, lot details matched, and the 50 mg dose makes it easy to treat several small zones in one session.
Used it for periorbital work where the standard 150 mg pack feels too coarse. Reconstitution was straightforward, the suspension stayed even through a 30G cannula, and the under-eye area settled without visible lumps.
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